Switch to anabolism and glucose metabolism	Switch to catabolism and fat metabolism
Glucose and fatty acid uptake by liver, adipose and muscle tissue	Reaction accelerated	Reaction inhibited
Secretion of glucose by liver and NEFA by adipose tissue	Reaction inhibited	Reaction accelerated
Protein kinase B – phosphodiesterase	Pathways accelerated	Pathways inhibited
Glycogenesis
TAG synthesis
FA biosynthesis
cAMP cascade – protein kinase A	Pathways inhibited	Pathways accelerated
Glycogenolysis
Lipolysis (TAG hydrolysis)
Beta-oxidation (FA oxidation)
Gluconeogenesis	Pathway inhibited	Pathway accelerated
Glycolysis	Pathways accelerated	Pathways inhibited
Pentose Phosphate Pathway